Publications 2021 Mechanically active integrins direct cytotoxic secretion at the immune synapse Mitchell S. Wang Yuesong Hu Elisa E. Sanchez Xihe Xie Nathan H. Roy Miguel de Jesus Weiyang Jin Joanne H. Lee Yeonsun Hong Minsoo Kim Lance C. Kam Khalid Salaita Morgan Huse Biphasic response of T cell activation to substrate stiffness Dennis J. Yuan Lingting Shi Lance C. Kam Multi-Factor Clustering Incorporating Cell Motility Predicts T Cell Expansion Potential Joanne H Lee Shuai Shao Michelle Kim Stacey M. Fernandes Jennifer R. Brown Lance C. Kam 2020 Modulating T Cell Activation Using Depth Sensing Topographic Cues Parthiv Kant Chauduri Mitchell S. Wang Charles T. Black Morgan Huse Lance C. Kam 4321 Personalization of T cell production for cellular immunotherapy Dennis Jinglun Yuan Shuai Shao Joanne H. Lee Stacey M. Fernandes Jennifer R. Brown Lance C. Kam Centrioles control the capacity, but not the specificity, of cytotoxic T cell killing Fella Tamzalit Diana Tran Weiyang Jin Vitaly Boyko Hisham Bazzi Ariella Kepecs Lance C. Kam Kathryn V. Anderson Morgan Huse 2019 T cell activation and immune synapse organization respond to the microscale mechanics of structured surfaces Weiyang Jin Fella Tamzalit Parthiv Kant Chaudhuri Charles T. Black Morgan Huse Lance C. Kam Cutting edge: synapse propensity of human memory CD8 T cells confers competitive advantage over naive counterparts Vivea Mayya David Deoil 1 , Lance C Kam 3 , Edard Juokusumo Enas Abu-Shah Willie Neiswanger Chirag Sachar David Deoil Lance C. Kam Michael L. Dustin Cutting Edge: Synapse Propensity of Human Memory CD8 T Cells Confers Competitive Advantage over Naive Counterparts Viveka Mayya Edward Judokusumo Enas Abu-Shah Willie Neiswanger Chirag Sachar David Depoil Lance C. Kam Michael L. Dustin Interfacial actin protrusions mechanically potentiate killing by cytotoxic T cells Fella Tamzalit Mitchell S. Wang Weiyang Jin Maria Tello-Lafoz Vitaly Boyko John M. Heddleston Charles T. Black Lance C. Kam Morgan Huse Interfacial actin protrusions mechanically enhance killing by cytotoxic T cells Fella Tamzalit Mitchell S. Wang Weiyang Jin Maria Tello-Lafoz Vitaly Boyko John M. Heddleston Charles T. Black Lance C. Kam Morgan Huse 2018 Ex vivo induction of regulatory T cells from conventional CD4+ T cells is sensitive to substrate rigidity Neha M. Nataraj Alex P. Dang Lance C. Kam Jounghyun H. Lee Mechanically induced Ca 2+ oscillations in osteocytes release extracellular vesicles and enhance bone formation Andrea E. Morrell Genevieve N. Brown Samuel T. Robinson Rachel L. Sattler Andrew D. Baik Gehua Zhen Xu Cao Lynda F. Bonewald Weiyang Jin Lance C. Kam X Edward Guo Enhanced activation and expansion of T cells using mechanically soft elastomer fibers Alex Dang Sarah De Leo Danielle R. Bogdanowicz Dennis J. Yuan Stacey M. Fernandes Jennifer R. Brown Helen H. Lu Lance C. Kam Durable interactions of T cells with T cell receptor stimuli in the absence of a stable immunological synapse Viveka Mayya Edward Judokusumo Enas Abu Shah Christopher G. Peel Willie Neiswanger David Depoil David A. Blair Chris H. Wiggins Lance C. Kam Michael L. Dustin 2017 Probing synaptic biomechanics using micropillar arrays Weiyang Jin Charles T. Black Lance C. Kam Morgan Huse Improving T cell expansion with a soft touch Lester H. Lambert Geraldine K E Goebrecht Sarah E. De Leo Roddy S. O'Connor Selene Nunez-Cruz Tai-De Li Jinglun Yuan Michael C. Milone Lance C. Kam 2016 Tapping out a mechanical code for T cell triggering Michael L. Dustin Lance C. Kam High-throughput mechanobiology screening platform using micro-and nanotopography Junqiang Hu Alexander A. Gondarenko Alex P. Dang Keenan T. Bashour Roddy S. O'Connor Sunwoo Lee Anastasia Liapis Saba Ghassemi Michael C. Milone Michael P. Sheetz Michael L. Dustin Lance C. Kam James C. Hone Cytotoxic T cells use mechanical force to potentiate target cell killing Roshni Basu Benjamin M. Whitlock Julien Husson Audrey Le Floc'h Weiyang Jin Alon Oyler-Yaniv Farokh Dotiwala Gregory Giannone Claire Hivroz Nicolas Biais Judy Lieberman Lance C. Kam Morgan Huse 2015 Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells Erdem Tabdanov Sasha Gondarenko Sudha Kumari Anastasia Liapis Michael L. Dustin Michael P. Sheetz Lance C. Kam Thomas Iskratsch A microfluidic platform reveals differential response of regulatory T cells to micropatterned costimulation arrays Joung-Hyun Lee Michael L. Dustin Lance C. Kam Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway Sudha Kumari David Depoil Roberta Martinelli Edward Judokusumo Guillaume Carmona Frank B. Gertler Lance C. Kam Christopher V. Carman Janis K. Burkhardt Darrell J. Irvine Michael L. Dustin 2014 Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse Kaushik Choudhuri Jaime Llodrá Eric W Roth Jones Tsai Susana Gordo Kai W Wucherpfennig Lance C. Kam David L Stokes Michael L Dustin 2012 Mechanosensing in T lymphocyte activation Edward Judokusumo Erdem Tabdanov Sudha Kumari Michael L. Dustin Lance C. Kam Featured Publication edit publication {{ name }} . . . Abstract Citation No resultsThere are no publications with the provided filters. Sort Publications By Keyword filter: {{ filter.label }}
Mechanically active integrins direct cytotoxic secretion at the immune synapse Mitchell S. Wang Yuesong Hu Elisa E. Sanchez Xihe Xie Nathan H. Roy Miguel de Jesus Weiyang Jin Joanne H. Lee Yeonsun Hong Minsoo Kim Lance C. Kam Khalid Salaita Morgan Huse
Biphasic response of T cell activation to substrate stiffness Dennis J. Yuan Lingting Shi Lance C. Kam
Multi-Factor Clustering Incorporating Cell Motility Predicts T Cell Expansion Potential Joanne H Lee Shuai Shao Michelle Kim Stacey M. Fernandes Jennifer R. Brown Lance C. Kam
Modulating T Cell Activation Using Depth Sensing Topographic Cues Parthiv Kant Chauduri Mitchell S. Wang Charles T. Black Morgan Huse Lance C. Kam
4321 Personalization of T cell production for cellular immunotherapy Dennis Jinglun Yuan Shuai Shao Joanne H. Lee Stacey M. Fernandes Jennifer R. Brown Lance C. Kam
Centrioles control the capacity, but not the specificity, of cytotoxic T cell killing Fella Tamzalit Diana Tran Weiyang Jin Vitaly Boyko Hisham Bazzi Ariella Kepecs Lance C. Kam Kathryn V. Anderson Morgan Huse
T cell activation and immune synapse organization respond to the microscale mechanics of structured surfaces Weiyang Jin Fella Tamzalit Parthiv Kant Chaudhuri Charles T. Black Morgan Huse Lance C. Kam
Cutting edge: synapse propensity of human memory CD8 T cells confers competitive advantage over naive counterparts Vivea Mayya David Deoil 1 , Lance C Kam 3 , Edard Juokusumo Enas Abu-Shah Willie Neiswanger Chirag Sachar David Deoil Lance C. Kam Michael L. Dustin
Cutting Edge: Synapse Propensity of Human Memory CD8 T Cells Confers Competitive Advantage over Naive Counterparts Viveka Mayya Edward Judokusumo Enas Abu-Shah Willie Neiswanger Chirag Sachar David Depoil Lance C. Kam Michael L. Dustin
Interfacial actin protrusions mechanically potentiate killing by cytotoxic T cells Fella Tamzalit Mitchell S. Wang Weiyang Jin Maria Tello-Lafoz Vitaly Boyko John M. Heddleston Charles T. Black Lance C. Kam Morgan Huse
Interfacial actin protrusions mechanically enhance killing by cytotoxic T cells Fella Tamzalit Mitchell S. Wang Weiyang Jin Maria Tello-Lafoz Vitaly Boyko John M. Heddleston Charles T. Black Lance C. Kam Morgan Huse
Ex vivo induction of regulatory T cells from conventional CD4+ T cells is sensitive to substrate rigidity Neha M. Nataraj Alex P. Dang Lance C. Kam Jounghyun H. Lee
Mechanically induced Ca 2+ oscillations in osteocytes release extracellular vesicles and enhance bone formation Andrea E. Morrell Genevieve N. Brown Samuel T. Robinson Rachel L. Sattler Andrew D. Baik Gehua Zhen Xu Cao Lynda F. Bonewald Weiyang Jin Lance C. Kam X Edward Guo
Enhanced activation and expansion of T cells using mechanically soft elastomer fibers Alex Dang Sarah De Leo Danielle R. Bogdanowicz Dennis J. Yuan Stacey M. Fernandes Jennifer R. Brown Helen H. Lu Lance C. Kam
Durable interactions of T cells with T cell receptor stimuli in the absence of a stable immunological synapse Viveka Mayya Edward Judokusumo Enas Abu Shah Christopher G. Peel Willie Neiswanger David Depoil David A. Blair Chris H. Wiggins Lance C. Kam Michael L. Dustin
Probing synaptic biomechanics using micropillar arrays Weiyang Jin Charles T. Black Lance C. Kam Morgan Huse
Improving T cell expansion with a soft touch Lester H. Lambert Geraldine K E Goebrecht Sarah E. De Leo Roddy S. O'Connor Selene Nunez-Cruz Tai-De Li Jinglun Yuan Michael C. Milone Lance C. Kam
High-throughput mechanobiology screening platform using micro-and nanotopography Junqiang Hu Alexander A. Gondarenko Alex P. Dang Keenan T. Bashour Roddy S. O'Connor Sunwoo Lee Anastasia Liapis Saba Ghassemi Michael C. Milone Michael P. Sheetz Michael L. Dustin Lance C. Kam James C. Hone
Cytotoxic T cells use mechanical force to potentiate target cell killing Roshni Basu Benjamin M. Whitlock Julien Husson Audrey Le Floc'h Weiyang Jin Alon Oyler-Yaniv Farokh Dotiwala Gregory Giannone Claire Hivroz Nicolas Biais Judy Lieberman Lance C. Kam Morgan Huse
Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells Erdem Tabdanov Sasha Gondarenko Sudha Kumari Anastasia Liapis Michael L. Dustin Michael P. Sheetz Lance C. Kam Thomas Iskratsch
A microfluidic platform reveals differential response of regulatory T cells to micropatterned costimulation arrays Joung-Hyun Lee Michael L. Dustin Lance C. Kam
Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway Sudha Kumari David Depoil Roberta Martinelli Edward Judokusumo Guillaume Carmona Frank B. Gertler Lance C. Kam Christopher V. Carman Janis K. Burkhardt Darrell J. Irvine Michael L. Dustin
Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse Kaushik Choudhuri Jaime Llodrá Eric W Roth Jones Tsai Susana Gordo Kai W Wucherpfennig Lance C. Kam David L Stokes Michael L Dustin
Mechanosensing in T lymphocyte activation Edward Judokusumo Erdem Tabdanov Sudha Kumari Michael L. Dustin Lance C. Kam